Table 3. The relationship between TNFAIP8L1 gene polymorphism and cervical cancer.
| SNP | Model | Genotype | Case | Control | Adjusted by age | |
|---|---|---|---|---|---|---|
| OR (95% CI) | P-value | |||||
| rs9917028 | Co-dominant | GG | 157 (46%) | 199 (40%) | 1 | |
| GA | 144 (42%) | 218 (44%) | 0.84 (0.62–1.13) | 0.241 | ||
| AA | 41 (12%) | 81 (16%) | 0.64 (0.42–0.99) | 0.044 | ||
| Dominant | GG | 157 (46%) | 199 (40%) | 1 | ||
| GA–AA | 185 (54%) | 299 (60%) | 0.78 (0.59–1.04) | 0.088 | ||
| Recessive | GG-GA | 301 (88%) | 417 (84%) | 1 | ||
| AA | 41 (12%) | 81 (16%) | 0.70 (0.47–1.05) | 0.087 | ||
| Additive | — | — | — | 0.81 (0.66–0.99) | 0.039 | |
| rs10426502 | Co-dominant | GG | 317 (93%) | 431 (83%) | 1 | |
| GA | 23 (6%) | 67 (17%) | 0.47 (0.28–0.76) | 0.003 | ||
| AA | 1 (1%) | 0 (0%) | — | 0.999 | ||
| Dominant | GG | 317 (93%) | 431 (83%) | 1 | ||
| GA-AA | 24 (7%) | 67 (17%) | 0.49 (0.30–0.79) | 0.004 | ||
| Recessive | GG-GA | 341 (91.90%) | 498 (100%) | 1 | ||
| AA | 1 (1%) | 0 (0%) | — | 0.999 | ||
| Additive | — | — | — | 0.52 (0.32–0.83) | 0.007 | |
| rs1060555 | Co-dominant | CC | 199 (58%) | 246 (49%) | 1 | |
| CG | 123 (36%) | 218 (44%) | 0.70 (0.52–0.93) | 0.015 | ||
| GG | 20 (6%) | 34 (7%) | 0.73 (0.41–1.30) | 0.285 | ||
| Dominant | CC | 199 (58%) | 246 (49%) | 1 | ||
| CG-GG | 143 (42%) | 252 (57%) | 0.70 (0.53–0.93) | 0.012 | ||
| Recessive | CC-CG | 322 (94%) | 464 (93%) | 1 | ||
| GG | 20 (6%) | 34 (7%) | 0.85 (0.48–1.50) | 0.571 | ||
| Additive | — | — | — | 0.77 (0.61–0.97) | 0.024 | |
P-values were calculated with wald-test. P<0.05 indicates statistical significance.