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. 2019 Jul 19;39(7):BSR20191155. doi: 10.1042/BSR20191155

Table 4. Relationships between TNFAIP8L1 and FLT1 polymorphism and cervical cancer risk according to the stratification by age.

SNP Model Genotype ≤43 >43
Gene OR (95% CI) P-value OR (95% CI) P-value
rs9917028 Allele G 1 1
TNFAIP8L1 A 0.75 (0.56–1.02) 0.064 0.84 (0.64–1.12) 0.238
Genotype GG 1 1
GA 0.94 (0.61–1.43) 0.766 0.75 (0.50–1.15) 0.187
AA 0.45 (0.22–0.91) 0.026 0.80 (0.46–1.40) 0.434
Dominant GG 1 1
GA-AA 0.81 (0.54–1.21) 0.305 0.77 (0.52–1.13) 0.180
Recessive GG-GA 1 1
AA 0.47 (0.24–0.91) 0.025 0.92 (0.55–1.55) 0.757
Additive 0.75 (0.56–1.02) 0.065 0.86 (0.66–1.13) 0.281
rs10426502 Allele G 1 1
TNFAIP8L1 A 0.62 (0.33–1.19) 0.149 0.44 (0.22–0.88) 0.017
Genotype GG 1 1
GA 0.53 (0.26–1.07) 0.077
AA 0.999
Dominant GG 1 1
GA-AA 0.57 (0.29–1.14) 0.112 0.42 (0.21–0.86) 0.017
Recessive GG-GA 1 1
AA 0.999
Additive 0.63 (0.33–1.22) 0.173 0.42 (0.21–0.86) 0.017
rs1060555 Allele C 1 1
TNFAIP8L1 G 0.86 (0.62–1.19) 0.355 0.72 (0.53–0.97) 0.033
Genotype CC 1 1
CG 0.94 (0.62–1.42) 0.760 0.54 (0.36–0.82) 0.003
GG 0.59 (0.22–1.60) 0.303 0.79 (0.38–1.64) 0.527
Dominant CC 1 1
CG-GG 0.89 (0.60–1.34) 0.583 0.58 (0.39–0.85) 0.005
Recessive CC-CG 1 1
GG 0.61 (0.23–1.62) 0.321 1.03 (0.50–2.10) 0.935
Additive 0.87 (0.61–1.22) 0.406 0.71 (0.52–0.97) 0.030
rs9513111 Allele T 1 1
FLT1 C 1.05 (0.78–1.41) 0.773 0.81 (0.61–1.08) 0.144
Genotype TT 1 1
TC 0.89 (0.58–1.36) 0.581 1.02 (0.68–1.54) 0.913
CC 1.38 (0.69–2.76) 0.359 0.55 (0.29–1.04) 0.067
Dominant TT 1 1
TC-CC 0.96 (0.64–1.44) 0.852 0.89 (0.61–1.31) 0.561
Recessive TT-TC 1 1
CC 1.47 (0.76–2.83) 0.250 0.54 (0.29–0.99) 0.049
Additive 1.06 (0.78–1.45) 0.695 0.82 (0.62–1.09) 0.166

P-values were calculated with wald-test. P<0.05 indicates statistical significance.