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. 2019 Jul 19;39(7):BSR20190280. doi: 10.1042/BSR20190280

Figure 5. Proposed model for the mechanism involving PFAR and miR-15a in lung fibrosis.

Figure 5

lncRNA PFAR promoted lung fibroblasts activation and ECM deposition via regulating of YAP1-Twist axis by acting as a sponge of miR-15a, whereas knockdown of PFAR exerted the anti-fibrotic effect.