Figure 4.

Equilibrium concentrations of angiotensin peptides (APs) of the renin‐angiotensin‐aldosterone system (RAAS) in control dogs (CTL) and dogs with stage B1, B2, and C heart disease. Ang1‐5, angiotensin 1‐5; Ang1‐7, angiotensin 1‐7; Ang1‐9, angiotensin 1‐9; Ang 2‐7, angiotensin 2‐7, Ang2‐10, angiotensin 2‐10; Ang3‐7, angiotensin 3‐7; AT1(1‐10), angiotensin I; AT2(1‐8), angiotensin II; AT3(2‐8), angiotensin III; AT4(3‐8), angiotensin IV. See text for description of the modified clinical staging system. *P < .05; **P < .01; ***P < .001; ****P < .0001