Figure 5.

Equilibrium concentrations of angiotensin peptides (APs) and angiotensin converting enzyme (ACE) and angiotensin‐converting‐enzyme 2 (ACE2) pathways within a broader view of the renin‐angiotensin‐aldosterone system (RAAS) permits evaluation of the relative concentration and relationship between the various APs. The sizes of the circles are proportional to the median equilibrium concentration (pg/mL) of each AP. See text for description of the modified clinical staging system. AmP, aminopeptidase; DAP, aspartyl aminopeptidase; NEP, neutral endopeptidase. Other abbreviations same as in Figure 4