Table 1.
Plasma amino acid concentrations in dogs with inflammatory bowel disease (IBD) and healthy control dogs
| Controls | IBD | P‐value | |
|---|---|---|---|
| n | 12 | 10 | |
| Alanine | 506.0 (403.8‐726.5) | 447.1 (244.7‐1190.7) | .64 |
| Arginine | 103.9 (69.9‐158.9) | 91.7 (53.7‐166.2) | .32 |
| Asparagine | 52.4 (40.7‐78.3) | 39.6 (23.9‐87.0) | .008 |
| Citrulline | 58.3 (22.2‐77.7) | 69.3 (27.5‐155.4) | .32 |
| Glutamic acid | 24.9 (14.1‐52.2) | 45.2 (32.6‐78.0) | .009 |
| Glutamine | 819.0 (588.5‐1003.4) | 508.7 (390.5‐1312.5) | .05 |
| Glycine | 233.4 (180.2‐335.3) | 160.7 (96.8‐305.9) | .02 |
| Histidine | 77.9 (67.7‐95.3) | 62.6 (47.6‐84.0) | .008 |
| Isoleucine | 62.7 (37.1‐72.2) | 54.8 (34.8‐90.0) | .84 |
| Leucine | 133.0 (61.4‐187.5) | 106.2 (70.2‐229.1) | .51 |
| Lysine | 127.6 (89.4‐177.9) | 137.7 (83.4‐286.2) | .79 |
| Methionine | 62.6 (51.0‐83.6) | 46.2 (30.0‐59.3) | <.001 |
| Ornithine | 15.7 (10.7‐31.2) | 19.7 (10.7‐33.2) | .51 |
| Phenylalanine | 65.9 (54.5‐75.2) | 59.8 (37.5‐71.7) | .13 |
| Proline | 199.1 (132.5‐376.7) | 119.4 (76.7‐189.2) | .001 |
| Serine | 164.3 (124.7‐222.9) | 115.1 (61.4‐155.9) | .001 |
| Taurine | 115.6 (69.6‐211.8) | 118.4 (53.4‐174.9) | .95 |
| Threonine | 206.2 (147.8‐444.8) | 118.7 (71.0‐215.4) | .005 |
| Tryptophan | 68.3 (35.7‐94.8) | 17.4 (11.9‐56.3) | .001 |
| Tyrosine | 54.6 (41.7‐81.5) | 40.6 (26.6‐60.3) | .003 |
| Valine | 169.7 (97.8‐230.0) | 153.2 (95.6‐378.3) | .74 |
| Total | 2982.8 (2264.6‐3899.3) | 2643.4 (1923.9‐4869.6) | .06 |
Notes: Data are presented as median (range). Amino acid concentrations are in nmol/mL.