Table 3.
Period 1 | Period 2 | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Baseline | Treatment | Baseline | Treatment | |||||||
Week 1 | Week 2 | Week 3 | Weeks 1‐3 | Week 1 | Week 2 | Week 3 | Weeks 1‐3 | |||
Group A | 1/11 | 7/11 | 8/10a | 4/10a | 11/11 | 1/11 | 4/11 | 5/10a | 4/10a | 8/11 |
Group B | 3/11 | 7/11 | 10/11 | 8/11 | 11/11 | 2/11 | 7/11 | 6/11 | 7/11 | 8/11 |
All dogs | 4/22 | 14/22 | 18/21 | 12/21 | 22/22 | 3/22 | 11/22 | 11/21 | 11/21 | 16/22 |
Dogs received enrofloxacin (10 mg/kg PO q24h) and metronidazole (12.5 mg/kg PO q12h), followed 1 hour later by either a placebo or probiotic/synbiotic combination PO. Dogs in group A received placebos during period 1 and probiotics in period 2, whereas dogs in group B received the probiotic/synbiotic combination during period 1 and placebos during period 2.
Data were not available for 1 dog due to removal from treatment.