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Heparin oligosaccharide products treated with heparanase Bp. Low sulfated domain will be cut by heparanase Bp and form a highly sulfated domain, which has a GlcA residue at the non-reducing end, and it cannot be IdoA/IdoA2S/GlcA2S, and GlcN at the reducing end, which can be modified to GlcNAc/GlcNAc6S/GlcNS, and it cannot be GlcNS6S/GlcNS6S3S.
