Table 2.

Odds Ratio of Risk of Future HIV Load >20 copies/mL by Concentration of Tenofovir Diphosphate in Dried Blood Spots at Current Visit (N = 697 Paired Assessments)

TFV-DP (fmol/punch)	Paired Assessments, n (%)	OR (95% CI)	P Value	aOR (95% CI)a	P Value
BLQ to <800	82 (12)	4.2 (2.3–7.5)	<.0001	4.7 (2.6–8.7)	<.0001
800 to <1650	247 (35)	1.8 (1.2–2.7)	.007	2.1 (1.3–3.3)	.002
≥1650	368 (53)	1	REF	1	REF

Abbreviations: aOR, adjusted odds ratio; BLQ, below limit of quantification; CI, confidence interval; OR, odds ratio; REF, reference; TFV-DP, tenofovir diphosphate.

^aAdjusted for age, sex, race, body mass index, estimated glomerular filtration rate, CD4⁺ T-cell count, and antiretroviral therapy class. The OR and aOR between categories BLQ to <800 vs 800 to <1650 fmol/punch were 2.3 (1.3–4.1), P = .003 and 2.3 (1.2–4.2), P = .008, respectively.