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. 2019 Apr 11;220(4):594–602. doi: 10.1093/infdis/jiz159

Figure 2.

Figure 2

Measles virus–specific neutralizing antibodies measured by a focus reduction neutralization test (FRNT) in children who received their first measles, mumps, and rubella vaccine (MMR) dose at 6–8 months, 9–12 months, or 14 months of age. Differences in geometric mean concentrations between groups, represented as horizontal bars, were compared by the Kruskal-Wallis test at 14 months of age (A) and then 6 weeks (B), 1 year (C), and 3 years later (D). The dashed gray line indicates the level of antibody sufficient for protection from clinical measles (ie, 0.12 IU/mL). Two controls assumed to have measles, based on positive serologic test results at 14 months of age, were excluded from analysis. MMR-1, MMR dose received at age 14 months. *P ≤ .05, **P ≤ .01, and ****P ≤ .0001.