Fig. 7.

DPI and apocynin inhibit superoxide anion generation, but not elastase release, in activated human neutrophils. Human neutrophils were incubated with DMSO, (A and C) DPI (3–300 nM), or (B and D) apocynin (3–300 μM) for 5 min, and then activated by fMLF/CB for another 10 min. (A and B) Superoxide anion and (C and D) elastase release were measured. All data are expressed as mean ± S.E.M. (n = 5). *p < 0.05; **p < 0.01; ***p < 0.001 compared with fMLF alone.