TABLE 3.

Results of inter-method reliability analysis comparing SERT occupancy (OCC) obtained from [¹¹C]DASB bolus PET scans using the multilinear reference tissue model (MRTM2) with SERT OCC obtained from [¹¹C]DASB bolus plus constant infusion PET/MR scans using the equilibrium method.

Region of interest	OCC PET/MR	SD	OCC PET	SD	Mean difference (%)	SD	MSB	MSE	ICC (ρ)
Frontal cortex	74.39	10.58	129.62	101.63	82.33	1.62	4914.872	5525.347	−0.06
Occipital cortex	48.62	16.25	53.57	30.35	7.88	0.54	977.247	208.188	0.65
Parietal cortex	68.22	23.99	146.24	170.46	145.30	2.81	14586.857	15045.049	−0.02
Temporal cortex	41.89	27.22	62.21	15.62	−42.61	1.74	674.947	309.764	0.37
Anterior cingulate cortex	52.86	20.48	54.74	17.37	23.64	0.80	513.258	207.879	0.42
Amygdala	52.61	8.43	78.07	10.04	53.19	0.40	55.212	116.635	−0.36
Olfactory cortex	52.45	13.54	71.03	6.62	44.35	0.46	167.682	59.646	0.48
Caudate nucleus	54.42	8.76	68.86	6.20	28.51	0.17	89.552	25.620	0.56
Putamen	52.34	10.82	64.38	6.73	26.75	0.23	145.719	16.746	0.79
Thalamus	51.81	9.38	63.78	5.94	26.11	0.23	97.240	26.147	0.58
Striatum	53.09	10.43	65.35	6.11	26.12	0.19	132.921	13.175	0.82
Midbrain	44.96	11.15	67.32	5.94	61.42	0.60	103.889	55.779	0.30