Figure 3.

Disease course for isolated IMN failures. Timeline of disease progression for the 10 patients who presented with isolated IMN failures. Bars indicate length of disease-free interval (white), isolated relapse (gray), and survival with distant metastases (black). Five patients had repeat IMN relapse after salvage treatments (1, 5, 6, 7, and 8). Four patients developed distant metastases (1, 6, 7, and 8), and there was 1 patient death (1, starred). The 3 patients with the longest overall survival (patients 8, 9, and 10) all received chemotherapy, surgery, and radiation for salvage treatment. Abbreviation: IMN = internal mammary lymph node.