Table 2.
Effect/variable | OR | 95% CI | P |
---|---|---|---|
Univariate model | |||
Clinical | |||
Age (units = 10 years) | 0.64 | 0.40–1.05 | 0.0760 |
Gender (female vs male) | 1.43 | 0.46–4.42 | 0.5362 |
Race (black/African American vs white) | 0.31 | 0.07–1.39 | 0.1272 |
Chronic Health Points score (units = 5) | 0.15 | 0.01–1.58 | 0.1143 |
Acute Physiology score (units = 10) | 0.32 | 0.12–0.84 | 0.0215 |
Total APACHE II score (units = 10) | 0.24 | 0.09–0.67 | 0.0064 |
Did fever go away ≤ 72 h? (No vs Yes) | 0.26 | 0.07–0.96 | 0.0424 |
Was surgery performed ≤ 30 days? (No vs Yes) | 3.93 | 1.03–14.99 | 0.0452 |
Duration of antibiotic treatment (units = 7 days) | 1.27 | 1.03–1.56 | 0.0259 |
Serologya | |||
NAb_AT | 1.90 | 0.87–4.15 | 0.1085 |
NAb_LukAB | 1.97 | 0.91–4.26 | 0.0857 |
IgG_AT | 2.64 | 1.05–6.63 | 0.0392 |
IgG_ClfA | 2.28 | 0.88–5.93 | 0.0899 |
IgG_ClfB | 2.20 | 0.78–6.23 | 0.1386 |
IgG_DT | 1.86 | 0.77–4.50 | 0.1658 |
IgG_FnbpA | 1.79 | 0.63–5.08 | 0.2751 |
IgG_LukAB | 2.47 | 0.95–6.42 | 0.0637 |
IgG_MntC | 1.17 | 0.60–2.31 | 0.6420 |
IgG_SdrC | 0.74 | 0.25–2.24 | 0.5977 |
IgG_TSST1 | 1.29 | 0.77–2.16 | 0.3284 |
IgM_AT | 1.37 | 0.31–5.99 | 0.6785 |
IgM_ClfA | 4.32 | 1.45–12.85 | 0.0086 |
IgM_ClfB | 2.17 | 0.82–5.73 | 0.1175 |
IgM_DT | 1.53 | 0.64–3.65 | 0.3378 |
IgM_FnbpA | 4.65 | 1.35–16.07 | 0.0151 |
IgM_LukAB | 1.12 | 0.44–2.81 | 0.8159 |
IgM_MnTc | 1.60 | 0.65–3.96 | 0.3044 |
IgM_SdrC | 10.10 | 2.04–49.92 | 0.0046 |
IgM_TSST1 | 1.31 | 0.55–3.13 | 0.5467 |
Staphylococcus aureus isolate | |||
Haemolytic activity (10‐fold increase) | 1.75 | 0.92–3.33 | 0.0903 |
AT ELISA (10‐fold increase) | 2.02 | 0.73–5.57 | 0.1731 |
MSSA vs MRSA | 1.78 | 0.55–5.77 | 0.3356 |
fnbA (negative vs positive) | 0.48 | 0.15–1.55 | 0.2195 |
hla (negative vs positive) | 0.50 | 0.10–2.35 | 0.3763 |
tst (negative vs positive) | 1.45 | 0.34–6.18 | 0.6175 |
Multivariate model | |||
Total APACHE II (score increase by 10) | 0.34 | 0.11–1.05 | 0.0605 |
Haemolytic activity (10‐fold increase) | 2.94 | 1.05–8.27 | 0.0409 |
IgM SdrC (10‐fold increase) | 13.95 | 1.18–164.49 | 0.0363 |
IgM ClfA (10‐fold increase) | 5.72 | 1.16–28.24 | 0.0322 |
MRSA, methicillin‐resistant S. aureus; MSSA, methicillin‐susceptible S. aureus.
Serology OR corresponds to a 10‐fold increase in antibody levels.