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. 2018 Dec 5;1(3):249–253. doi: 10.1002/agm2.12046

Table 1.

SNPs identified for IL‐18, IL‐1‐ra, IL‐6, and ESR from current literature

Biomarker Chromosome Position SNP IGAP effect allele Biomarker effect allele Minor allele frequency Variance explained (%)
IL‐18 2 32489851 rs385076 C C 0.34 2.65
IL‐18 11 112085316 rs2250417 T T 0.48 0.50
IL‐1ra 2 113834820 rs13386602 A A 0.44 0.83
IL‐1ra 2 113832333 rs6743376 A A 0.43 0.83
IL‐1ra 2 113874467 rs4251961 T T 0.32 0.29
IL‐6 14 52083080 rs1008924 A A 0.507 0.62
IL‐6 1 154426264 rs4129267 T A 0.41 0.31
IL‐6 9 136142355 rs643434 G G 0.742 2.30
ESR 1 207803021 rs11803956 T T 0.752 0.88
ESR 16 78019687 rs11861089 C T 0.694 0.57
ESR 1 207739127 rs3886100 A A 0.772 0.89
ESR 11 5306509 rs4910742 G A 0.934 0.65

ESR, erythrocyte sedimentation rate; IGAP, International Genomics of Alzheimer's Project; IL, interleukin; SNPs, single nucleotide polymorphisms.