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. Author manuscript; available in PMC: 2019 Jul 19.
Published in final edited form as: Nature. 2016 Oct 6;539(7627):48–53. doi: 10.1038/nature20122

Figure 3. Binding of pArgAA to ClpC.

Figure 3

a, b, Inhibitory effect of pArgAA on McsBA-activated (a) and MecA-activated (b) ClpCP. c, Pull-down experiment monitoring the interaction of the NTD (wild type and E32A/E106A mutant) with MecA (10 μM each) in the presence pArgAA. d, ITC profile of pArgAA binding to full-length double Walker B mutant ClpC (ClpCDWB(FL); left) and the NTD of ClpC (ClpCNTD(1–150); right). Determined Kd values are indicated.