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. Author manuscript; available in PMC: 2020 Jul 22.
Published in final edited form as: Angew Chem Int Ed Engl. 2019 Jun 24;58(30):10245–10249. doi: 10.1002/anie.201905021

Figure 2.

Figure 2.

Diversification of product 8f. Reagents and conditions [1] (i) Rh/Al2O3 (cat.), H2, 96%; (ii) α–bromoacetophenone, K2CO3, 56%; (iii) KOH, 95%; [2] Li, NH3, 83%; [3] (i) Rh/Al2O3 (cat.), H2, 96%; (ii) HCl, 59%; [4] (i) Rh/Al2O3 (cat.), H2, 96%; (ii) tBuOCl, AcOH, 73%; [5] (i) Rh/Al2O3 (cat.), H2, 96%; (ii) tBuOCl, 68%.