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Holo is in blue and bound is in red. The co-crystallized ligand position is in green and the predicted ones are in orange. (A) Bcl2 in ligand-bound (4lvt) and protein-bound conformation (2xa9). (B) Mdmx in ligand-bound (3lbj) and protein-bound conformation (3dab). (C) The von Hippel–Lindau protein in ligand-bound (4b9k) and protein-bound conformation (4ajy).
