Table 2:
Potential antigens/immunogens for vaccines for three major autoimmune diseases.
| RA | MS | T1D |
|---|---|---|
| Collagen | Myelin | Insulin/pre/pro-insulin |
| Proteoglycan (PG) | Proteolipid protein (PLP) | Islet-specific glucose-6-phosphatase catalytic subunit related protein |
| Vimentin, filaggrin, fibrinogen | Myelin oligodendrocyte glycoprotein (MOG) | Tyrosine phosphatase like protein |
| Heat shock proteins (HSP) | Glutamic acid decarboxylase (GAD65) | |
| Nuclear proteins | Human islet amyloid polypeptide precursor protein | |
| Citrullinated proteins | Citrullinated proteins |