Table 5.
Risk of bias assessment of randomized controlled studies on 100% fruit juice and dental health.
| References | Randomized | Sequence generation | Allocation concealment | Blinding | Analysis population | Analysis approach | Incomplete data | Dropouts (%) | Funding |
|---|---|---|---|---|---|---|---|---|---|
| EROSION | |||||||||
| Dever et al. (21) | nr | nr | nr | nr | Completers | Paired t-test, adjusted for unequal variances. No other confounder adjustments reported | nr | 37.5% | nr |
| West et al. (30) | Yes | nr | nr | Single | ITT | Paired non-parametric Wilcoxon, No adjustments |
n/a | 0% | Industry |
| Hughes et al. (31) | Yes, balanced for residual effects | nr | nr | Single | ITT | Paired t-test No reported adjustments |
n/a | 0% | nr |
| West et al. (32) | Yes | nr | nr | Single | ITT | Paired t-test No reported adjustments |
n/a | 0% | nr |
| Hughes et al. (33) | Yes | nr | nr | Single | ITT | ANOVA paired t-test between beverages subjects, period, treatment used in statistical models | n/a | 0% | nr |
| Finke et al. (34) | Yes, balanced for 1st order crossover effects | nr | nr | Single | nr | 3-way ANOVA and multiple range test (Fisher's LSD) drinks, exposure time, volunteers used in statistical models | nr | nr | Industry & Government Grant Funded |
| CARIES AND MINERALIZATION | |||||||||
| Tenovuo and Rekola (35) | nr | nr | nr | nr | ITT | Student's t-test | n/a | 0% | Industry |
| Jensen et al. (36) | Yes | nr | nr | nr | nr | ANOVA followed by Tukey's protected t-test No reported adjustments |
nr | 20% | nr |
| Issa et al. (37) | Partial at lab site only | nr | nr | Single at lab site | nr | Paired t-test, 1-way ANOVA, post-hoc Tukey's test for multiple comparisons No reported adjustments |
nr | nr | Industry |
d, day; ITT, intent-to-treat; n/a, not applicable; nr, not reported.