Figure 3.

Sequence alignment of Iad2 with Iad1 and Pad2. Identical amino acids are boxed and shaded. Gaps have been inserted to increase the number of identities. Asterisks mark highly conserved amino acid residues described to be implicated in catalytic activity (E₂₅₃), substrate binding (C₂₈₈) and NAD binding (K₁₈₀, G₂₃₁, G₂₃₆; numbers refer to Iad2). Dots mark amino acids shared between Iad1 and Iad2 and absent from all remaining predicted aldehyde dehydrogenase sequences of U. maydis (see Discussion).