Figure 3.

Oomycete Avh proteins have a modular structure. (a) Avh shows the basic components of an RXLR‐dEER protein, with an N‐terminal signal peptide (SP), the RXLR‐dEER domain and the C‐terminus with a variable number of modules that consist of W, Y and L motifs. PiAvr4 carries three W motifs and one Y motif. Avr3a, shown as an example of another Phytophthora infestans Avr protein, carries only a single W motif. (b) A schematic representation of the relative positions and sizes of the conserved motifs in PiAvr4 and the building blocks that were used to generate deletion constructs. Building block [SPRD] covers the SP (hatched) and the RXLR and dEER motifs (black). [W1], [W2] and [W3Y] cover the W motifs (dark grey) and the Y motif (light grey).