Table 1.
Summary of weight loss, urinary output and urinary biomarkers
| Control | Vancomycin | P value | |
|---|---|---|---|
| Animals (n) | 5 | 45 | – |
| Baseline weight (g), mean ± SD | 323.8 ± 22.42 | 312.87 ± 15.37 | 0.16 |
| Weight loss (g), mean ± SD | 4.8 ± 2.28 | 8.6 ± 8.95 (n = 40)a | 0.35 |
| Urine output (mL), mean ± SD | 16.86 ± 3.07 | 15.74 ± 4.48 (n = 41)a | 0.59 |
| KIM-1 (ng/mL), median (IQR) | 1.02 (0.88–1.05) | 12.3 (5.6–13.9) (n = 43)b | <0.001 |
| Clusterin (ng/mL), median (IQR) | 319.5 (308.9–332.2) | 879.4 (617.6–1362) (n = 43)b | 0.0043 |
| OPN (ng/mL), median (IQR) | 0.02 (0.01–0.03) | 0.218 (0.11–0.39) (n = 43)b | <0.001 |
a
Some values inadvertently not recorded.
b
For animals completing the urine endpoint.