Table 1.
Number of genes in glycolytic and other pathways.
| Pathway and enzymatic activity* | Symbol | Number of predicted genes† | |||||
|---|---|---|---|---|---|---|---|
| P. infestans | P. ramorum | Yeast | Arabidopsis | Diatom | Human | ||
| Glycolysis | |||||||
| Invertase (EC 3.2.1.26) | INV | 3 | 3 | 6 | 11 | 0 | 1 |
| Hexokinase (EC 2.7.1.2) | HXK | 5‡ | 4 | 4 | 6 | 1 | 4 |
| Glucose‐6‐phosphate isomerase (EC 5.3.1.9) | GPI | 1 | 1 | 1 | 2 | 2 | 2 |
| 6‐Phosphofructokinase (EC 2.7.1.11) | FPK | 1 | 1 | 2 | 7 | 2 | 3 |
| Fructose‐bisphosphate aldolase (EC 4.1.2.13) | ALD | 3 | 3 | 1 | 2 | 4 | 3 |
| Triosephosphate isomerase (EC 5.3.1.1) | TPI | 2 | 2 | 1 | 2 | 4 | 3 |
| TPI + GPD gene fusion | TPI‐GPDH | 1 | 1 | 0 | 0 | 2 | 0 |
| Glyceraldehyde‐3‐phosphate dehydrogenase (EC 1.2.1.12) | GPDH | 7‡ | 6 | 3 | 8 | 3 | 2 |
| Phosphoglycerate kinase (EC 2.7.2.3) | PGK | 2 | 2 | 1 | 3 | 5 | 1 |
| Phosphoglycerate mutase (EC 5.4.2.1)§ | PGM | 2 | 2 | 3 | 3 | 10 | 2 |
| Enolase (phosphopyruvate hydratase; EC 4.2.1.11) | ENO | 4 | 3 | 2 | 3 | 2 | 4 |
| Pyruvate kinase (EC 2.7.1.40) | PYK | 6‡ | 7 | 2 | 14 | 5 | 2 |
| Gluconeogenesis‐related | |||||||
| Pyruvate carboxylase (EC 6.4.1.1) | PYC | 1 | 1 | 2 | 3 | 2 | 1 |
| Malate dehydrogenase (EC 1.1.1.37) | MDH | 2 | 2 | 3 | 10 | 3 | 1 |
| Phosphoenolpyruvate carboxykinase (EC 4.1.1.49) | PEPCK | 4 | 4 | 1 | 2 | 1 | 0 |
| Fructose‐1,6‐bisphosphatase (EC 3.1.3.11) | FBP | 1 | 2 | 1 | 3 | 3 | 2 |
| Other | |||||||
| Pyruvate, phosphate dikinase (EC 2.7.9.1) | PPDK | 2 | 2 | 0 | 1 | 1 | 0 |
| 6‐Phosphofructose‐2‐kinase (EC 2.7.1.105)¶ | PFK2 | 3 | 3 | 2 | 7 | 1 | 4 |
*
Some enzymes may also function in other pathways.
†
Number of predicted genes from Phytophthora, Saccharomyces (yeast), Arabidopsis thaliana, Thalassiosira pseudonana (diatom) and Homo sapiens (human). Phytophthora genes were manually annotated, whereas those in the other genomes were taken from their public assemblies.
‡
Includes one apparent pseudogene.
§
Does not include the seven apparent non‐glycolytic mutases.
¶
Bifunctional enzyme that also contains fructose‐2,6‐bisphosphate 2‐phosphatase activity (EC 2.7.1.11).