Table 3.
Calcium‐handing properties of mES‐CM in co‐culture
| mES‐CM | Direct Co‐culture | |||
|---|---|---|---|---|
| Untreated | LPS‐treated | IL‐4‐treated | ||
| 24 h | ||||
| N, n | 3, 33 | 3, 25 | 3, 16 | 3, 29 |
| Amp, F/F 0 | 1.2 ± 0.1 | 1.31 ± 0.17* | 1.29 ± 0.15 | 1.48 ± 0.19* , ‡ , § |
| T 50, msec | 133.6 ± 59.0 | 138.0 ± 52.5 | 225.2 ± 124.8 | 188.9 ± 105.5 |
| CI Amp, F/F 0 | 1.9 ± 0.4 | 1.94 ± 0.58 | 2.24 ± 0.63 | 2.45 ± 0.58* , ‡ |
| CI T50, msec | 1817.5 ± 1618.9 | 1377.6 ± 655.8 | 1515.7 ± 891.8 | 1193.9 ± 602.0 |
| 72 h | ||||
| N, n | 6, 45 | 6, 19 | 6, 31 | 6, 22 |
| Amp, F/F 0 | 1.3 ± 0.2‡ | 1.63 ± 0.37 | 1.24 ± 0.15‡ | 1.36 ± 0.14‡ , § |
| T 50, msec | 136.9 ± 91.6 | 180.1 ± 70.3 | 129.1 ± 47.6‡ | 169 ± 88.7 |
| CI Amp, F/F 0 | 2.2 ± 0.4 | 2.36 ± 0.52 | 2.11 ± 0.46 | 2.07 ± 0.35 |
| CI T 50, msec | 1335.6 ± 762.8‡ | 914.1 ± 427.7 | 1376.4 ± 693.2‡ | 1025.4 ± 287.0 |
Values are mean ± SD. N, independent trials; n, cell number; Amp, paced transient amplitude; T 50, paced transient T 50; CI Amp, caffeine‐induced transient amplitude; CI T 50, caffeine‐induced transient T 50; One‐way ANOVA and Tukey or Kruskal–Wallis and Games‐Howell; *P < 0.05 versus monoculture; ‡ P < 0.05 versus untreated; § P < 0.05 versus LPS‐treated.