Table 1.

Sphingolipid metabolism.

Metabolite	Fold change (MOTS‐c/Water)	P value	q value
Sphinganine	0.78	0.1213	0.3993
Sphinganine‐1‐phosphate**	0.73	0.021	0.196
N‐palmitoyl‐sphinganine (d18:0/16:0)	0.97	0.6427	0.6597
Palmitoyl dihydrosphingomyelin (d18:0/16:0)*	0.86	0.0573	0.3038
Behenoyl dihydrosphingomyelin (d18:0/22:0)	0.81	0.6022	0.6489
Palmitoyl sphingomyelin (d18:1/16:0)**	0.77	0.0067	0.1694
Stearoyl sphingomyelin (d18:1/18:0)**	0.63	0.0043	0.1694
Behenoyl sphingomyelin (d18:1/22:0)	0.85	0.7479	0.6902
Tricosanoyl sphingomyelin (d18:1/23:0)	0.93	0.7554	0.6902
Lignoceroyl sphingomyelin (d18:1/24:0)	1	0.9763	0.7374
Sphingomyelin (d18:1/14:0, d16:1/16:0)	0.8	0.2026	0.4862
Sphingomyelin (d18:2/14:0, d18:1/14:1)	0.62	0.1207	0.3993
Sphingomyelin (d18:1/15:0, d16:1/17:0)	0.9	0.4149	0.5865
Sphingomyelin (d18:2/16:0, d18:1/16:1)	0.83	0.1824	0.4641
Sphingomyelin (d18:1/17:0, d17:1/18:0, d19:1/16:0)	0.8	0.1202	0.3993
Sphingomyelin (d18:1/18:1, d18:2/18:0)**	0.74	0.0166	0.1826
Sphingomyelin (d18:1/20:0, d16:1/22:0)	0.66	0.2244	0.4896
Sphingomyelin (d18:1/20:1, d18:2/20:0)	0.72	0.1656	0.4492
Sphingomyelin (d18:1/21:0, d17:1/22:0, d16:1/23:0)	0.92	0.9414	0.7258
Sphingomyelin (d18:1/22:1, d18:2/22:0, d16:1/24:1)	0.76	0.3585	0.5592
Sphingomyelin (d18:2/23:0, d18:1/23:1, d17:1/24:1)	0.81	0.3329	0.5438
Sphingomyelin (d18:1/24:1, d18:2/24:0)**	0.74	0.0056	0.1694
Sphingomyelin (d18:2/24:1, d18:1/24:2)**	0.71	0.0007	0.0727
Sphingosine	0.95	0.8005	0.6929
Sphingosine 1‐phosphate**	0.86	0.022	0.196
N‐palmitoyl‐sphingosine (d18:1/16:0)	0.88	0.436	0.5946
N‐stearoyl‐sphingosine (d18:1/18:0)	0.92	0.7263	0.6829
Glycosyl‐N‐palmitoyl‐sphingosine*	0.76	0.088	0.3449
Glycosyl‐N‐stearoyl‐sphingosine*	0.6	0.0756	0.3226
Lactosyl‐N‐palmitoyl‐sphingosine	0.62	0.1816	0.4641

Bold indicates significant difference *P < 0.05 and **0.05 <P <0.10.