Table 5.

Medium effects involved in the dissociation of protonated tris(hydroxymethyl)aminomethane in water-methanol solvents at 25 °C

Wt percent methanol	30	50	70	90
psK — pwK	−0.132	−0.247	−0.217	+ 0.390
log mγB	.180	.343	.604	1.032
log mγHCl	.162	.268	.456	0.920
log mγB·HCl	.319	.563	.867	1.240
log mγLiCl	.361	.620	.936	1.369
${\Delta }_{\text{m}}{G}_{\text{B·HCl}}^{°}\left(\text{kJ\hspace{0.17em}}{\text{mol}}^{-1}\right)$	3.64	6.43	9.90	14.16