Fig. 4.

Mitochondrial respiration parameters of INS-1 832/13 cells after 24-h exposure to iAs^III or MAs^III. OCR was measured in INS-1 832/13 cells following 24-h exposure to iAs^III or MAs^III. Maximal respiration (a), spare respiratory capacity (b), non-mitochondrial respiration (c), and proton leak (d) were measured following sequential addition of: 16.7 mM glucose, oligomycin, FCCP, and a Rotenone/Antimycin A mix. Mean + SD is shown for six to seven technical replicates with two biological replicates. *p < 0.05, ⁺p < 0.01 for comparison of treated versus control cells