Table 1.
VHH CDR3 sequences of specific single domain antibodies.
| Nanobody | CDR3 Sequence | B-Yamagata | B-Victoria |
|---|---|---|---|
| Vic2b-3 | AADAVVAGPDDEYDY | + | + |
| Yam2a-10 | NVGFNY | + | + |
| Vic2a-20 | ASKGTDYIDGIYYISYQFNS | + | + |
| Vic2a-6 | VASPFSTGRATLPYQYPY | − | + |
| YamNGS#1 | AAASLCSFSSNDYFY | + | − |
| Yam2b-9 | AAGSGGRYDY | + | + |
| Vic1b-10 | NAPTYSN | + | + |
| Yam1b-9 | ALGDFTGLTNLRQAFYDF | + | + |
| Yam2a-1 | NFPRSSS | + | + |
| Yam2c-16 | NTHDY | + | + |
| Vic2c-8 | ALGDFSGSLWAYEYDF | + | + |
| Yam1b-6 | AAAKGGGAYSMISAYTY | + | + |
| Yam2b-2 | RLDHWLVSGY | + | + |
Binding to recombinant HA0 from the B-Victoria strain (B/Brisbane/60/2008) and the B-Yamagata strain (B/Florida/04/2006) in ELISA, indicated as binding (+) or not binding (−).