Table 1.
ID | Subclass | Monomer (%) | Mass (Da) | Glycoform Level (%) * | ||
---|---|---|---|---|---|---|
G0F |
G1F |
G2F |
||||
mAb 1 | IgG1 | >99 | 148,480 | 49 | 43 | 8 |
IgG2 | >99 | 147,913 | 52 | 39 | 9 | |
IgG4 | >99 | 148,190 | 45 | 39 | 16 | |
IgG4Pro | >99 | 148,210 | 43 | 40 | 17 | |
mAb 2 | IgG1 | >99 | 148,301 | 45 | 42 | 13 |
IgG2 | >99 | 147,734 | 50 | 41 | 9 | |
IgG4 | >99 | 148,012 | 43 | 43 | 14 | |
IgG4Pro | >99 | 148,032 | 20 | 50 | 30 | |
mAb 3 | IgG1 | >99 | 149,959 | 30 | 52 | 18 |
IgG2 | >99 | 149,231 | 45 | 41 | 14 | |
IgG4 | >99 | 149,507 | 49 | 43 | 8 | |
IgG4Pro | >99 | 149,529 | 25 | 52 | 25 |
* N-acetylglucosamine ■; mannose ●; galactose ►; fucose.