6HIS	hexa-histidine
ADA	anti-drug antibody
ADCC	antibody dependant cellular cytotoxicity
ADCP	antibody dependant cellular phagocytosis
ADH1	alcohol dehydrogenase 1
AIEX	anion exchange chromatography
ALI	acute lung inflammation
ARDS	acute respiratory distress syndrome
aTTP	acquired thrombotic thrombocytopenic purpura
ALL	acute lymphoblastic leukaemia
AMD	age-related macular degeneration
AML	acute myeloid leukaemia
BBB	blood–brain barrier
BCMA	B-cell maturation antigen
BiKE	bispecific natural killer cell engager
BiTE®	bispecific T-cell engager
CDC	complement-dependent cytotoxicity
CDR	complementarity determining region
CEA	carcinoembryonic antigen
CHO	Chinese hamster ovary
CIEX	cation exchange chromatography
CL	constant domain of immunoglobulin light chain
CNS	central nervous system
CPP	cell penetrating peptide
dAb	Domain antibody®
DART®	dual affinity re-targeting protein
EpCAM	epithelial cell adhesion molecule
ER	endoplasmic reticulum
Fab	fragment of antigen binding
Fc	fragment crystallizable
FcRn	neonatal fragment crystallizable receptor
Fv	fragment variable
GAPDH	glyceraldehyde-3-phosphate dehydrogenase
GFP	green fluorescent protein
GM-CSF	granulocyte-monocyte colony stimulating factor
GST	glutathione-S transferase
HAVH	human anti-VH
HEK	human embryonic kidney
HER2	human epidermal growth factor 2
HIC	hydrophobic interaction chromatography
HIV	human immunodeficiency virus
HLA	human leukocyte antigen
IgG	immunoglobulin gamma
IMAC	immobilised metal affinity chromatography
ImmTAC®	immune mobilising monoclonal t-cell receptors against cancer
ImmTAV®	immune mobilising monoclonal t-cell receptors against virus antigens
mAb	monoclonal antibody
MBP	mannose binding protein
MDS	myelodysplastic syndrome
MDSC	myeloid derived suppressor cell
MG	myasthenia gravis
MHC	major histocompatibility complex
MS	multiple sclerosis
Nb	Nanobody®
NK cell	Natural killer cell
NY ESO	New York esophageal squamous cell carcinoma
PD	pharmacodynamic
PEG	polyethylene glycol
PGK1	phosphoglycerate kinase 1
RMT	receptor-mediated endocytosis
RSV	respiratory syncytial virus
scFv	single chain fragment variable
SEC	size exclusion chromatography
SLE	systemic lupus erythematosus
TBGP	anti-trophoblast glycoprotein 5T4
TCR	T-cell receptor
TfR	transferrin receptor
TNF	tumour necrosis factor
IL	interleukin
TNFR1	tumour necrosis factor receptor 1
TriKE	trispecific natural killer cell engager
VEGF	vascular endothelial growth factor
VH	variable domain of immunoglobulin heavy chain
VL	variable domain of immunoglobulin light chain
V-NAR	variable new antigen receptor
vWF	von Willebrand factor