Table 2.
Coefficients and features of three radiomic signatures for pCR
| Coefficients | Features |
|---|---|
| Radiomic signature 1 (Sig 1) | |
| −0.283 (β0) | constant |
| −0.122 (β1) | bin32_original_shape_SurfaceVolumeRatio (x1) |
| −0.139 (β2) | bin32_log.sigma.2.5.mm.3D_firstorder_90Percentile (x2) |
| 0.160 (β3) | bin32_wavelet.LLH_GLRLM_ZoneEntropy (x3) |
| 0.181 (β4) | bin32_wavelet.HHH_GLRLM_RunEntropy (x4) |
| 0.012 (β5) | bin32_wavelet.LLL_GLRLM_RunVariance (x5) |
| Radiomic signature 2 (Sig 2) | |
| −0.288 (β0) | constant |
| −0.014 (β1) | bin64_log.sigma.2.5.mm.3D_firstorder_90Percentile (x1) |
| −0.054 (β2) | bin64_wavelet.LHH_GLSZM_LowGrayLevelZoneEmphasis (x2) |
| 0.068 (β3) | bin64_wavelet.LLH_GLSZM_ZoneEntropy (x3) |
| 0.210 (β4) | bin64_wavelet.HLH_GLRLM_RunVariance (x4) |
| 0.131 (β5) | bin64_wavelet.HHH_GLRLM_LongRunEmphasis (x5) |
| 0.015 (β6) | bin64_wavelet.HHH_GLRLM_RunEntropy (x6) |
| Radiomic signature 3 (Sig 3) | |
| −0.312 (β0) | constant |
| −0.028 (β1) | bin128_log.sigma.2.5.mm.3D_firstorder_90Percentile (x1) |
| −0.143 (β2) | bin128_log.sigma.2.5.mm.3D_GLRLM_ShortRunLowGrayLevelEmphasis (x2) |
| 0.247 (β3) | bin128_wavelet.HLH_GLRLM_RunVariance (x3) |
| 0.116 (β4) | bin128_wavelet.HHH_GLRLM_LongRunEmphasis (x4) |
| −0.011 (β5) | bin128_wavelet.HHL_GLCM_ClusterProminence (x5) |
| −0.024 (β6) | bin128_wavelet.HHL_GLSZM_ZonePercentage (x6) |
pCR = pathologic complete response, Filter “Wavelet”, H = high-pass filter (applied in the x, y and z directions, respectively), L = low-pass filter (applied in the x, y and z directions, respectively), pCR = pathologic complete response, GLCM = Gray Level Cooccurrence Matrix, GLSZM = Gray Level Size Zone Matrix, GLRLM = Gray Level Run Length Matrix.