Table 4. Recycling Studies for the Isomerization Reaction of 1a.
trial 1,a yield (%)b | trial 2,c yield (%)b | trial 3,d yield (%)b | |
---|---|---|---|
cycle 1 | 81 | 81 | 80 |
cycle 2 | 68 | 78 | 74 |
cycle 3 | 64 | 29 | 72 |
cycle 4 | 0 | 2 | 24 |
PdCl2 (5 mol %); reactions conducted in CH2Cl2 at 25 °C for 5 h for each cycle. All operations were under an atmosphere of N2.
Isolated yield of 1b.
PdCl2 (10 mol %); reactions conducted in CH2Cl2 at 25 °C for 5 h for each cycle.
PdCl2 (20 mol %); reactions conducted in CH2Cl2 at 25 °C for 2 h for each cycle.