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. 2017 Jan 12;2(1):91–97. doi: 10.1021/acsomega.6b00479

Table 1. Conversion and e.e. of the Alkylation Reaction of 1 with 2 in the Presence of Self-Assembliesa.

entry amphiphile (assembly) medium conv. (%) e.e. (%) (S–R)
I TBAH water/CH2Cl2 94 ± 2 –3 ± 3
IIb TBAH water 17 ± 6 –6 ± 7
III CTAB (micelle) water 95 ± 2 5 ± 3
IV DOPC (liposome) water 62 ± 5 97 ± 1
a

Unless otherwise notified, all reactions were carried out in water at room temperature (r.t.) for 24 h. [1] = 1.0 mM, [2] = 12 mM, [amphiphiles] = 10 mM, and [NaOH] = 0.3 M.

b

TBAH in water does not form any particular assembly. Independent experiments were conducted at least three times to calculate the values of conversion and e.e.