Table 1. Prognostic values of MCM genes expression in LUAD cohort of TCGA.

Genes	Expression level	Event/Total	MST	Crude HR(95%CI)	Crude P	Adjusted HR(95%CI)	Adjusted P&
SRF	Low	88/250	1498	1		1
	High	94/250	1421	1.125(0.840–1.505)	0.43	1.091(0.812–1.467)	0.563
MCM2	Low	80/250	1653	1		1
	High	102/250	1258	1.390(1.036–1.864)	0.028	1.196(0.887–1.613)	0.24
MCM3	Low	84/250	1501	1		1
	High	98/250	1293	1.197(0.894–1.603)	0.227	1.178(0.877–1.583)	0.276
MCM4	Low	77/250	1653	1		1
	High	105/250	1229	1.585(1.180–2.128)	0.002	1.362(1.008–1.842)	0.044
MCM5	Low	69/250	1790	1		1
	High	113/250	1171	1.842(1.365–2.486)	< 0.0001	1.579(1.163–2.143)	0.003
MCM6	Low	77/250	1653	1		1
	High	105/250	1288	1.464(1.090–1.966)	0.011	1.294(0.960-.745)	0.091
MCM7	Low	75/250	1622	1		1
	High	107/250	1265	1.516(1.128–2.038)	0.006	1.226(0.904–1.664)	0.191
MCM8	Low	83/250	1725	1		1
	High	99/250	1235	1.552(1.156–2.085)	0.003	1.391(1.003–1.873)	0.030
MCM9	Low	95/250	1498	1		1
	High	87/250	1499	0.990(0.740–1.325)	0.948	1.089(0.810–1.464)	0.573
MCM10	Low	79/250	1600	1		1
	High	103/250	1288	1.414(1.055–1.897)	0.021	1.237(0.917–1.669)	0.163

Notes: &Adjusted for tumor stage. MST, median survival time; HR, hazard ratio; CI, confidence interval; NA, not available; MCM, minichromosome maintenance; TCGA, The Cancer Genome Atlas.