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. 2019 Jul 19;14(7):e0220158. doi: 10.1371/journal.pone.0220158

Table 3. Baseline adiponectin level (continuous variable, log transformed) and outcomes.

RRT Composite renal outcome All-cause mortality
HR (95%CI)* P HR (95%CI)* P HR (95%CI)* P
Unadjusted 1.98 (1.17–3.39) 0.01 1.77
(1.19–2.63)
0.005 1.98
(1.05–3.72)
0.04
Adjusted
 Model 1b 1.94 (1.10–3.43) 0.02 1.69
(1.11–2.59)
0.02 1.10
(0.53–2.27)
0.80
 Model 2c 2.08 (1.17–3.72) 0.01 1.78
(1.15–2.75)
0.01 1.04
(0.49–2.22)
0.91
 Model 3d 2.08 (1.08–4.02) 0.03 1.66 (1.03–2.65) 0.04 0.93 (0.41–2.10) 0.86

*Per unit increase in log-transformed adiponectin

b Adjusted for age, gender, BMI, gout

c Adjusted for model 1 covariates plus metabolic syndrome criteria: (1) central obesity (waist circumference ≥ 90 cm in men or ≥ 80 cm in women, according to the ethnic criteria for Asians); (2)TG ≥ 150 mg/dL; (3) HDL cholesterol < 40 mg/dL in men and < 50 mg/dL in women; (4) fasting glucose ≥ 100 mg/dL or previously diagnosed with type 2 DM; (5) BP ≥ 130/85 mmHg or on treatment for hypertension

d Adjusted for model 2 covariates plus Hb, Albumin, CRP, eGFR, UPCR

Values expressed as hazard ratios (HR) and 95% confidence interval (CI).