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. 2019 Jul 19;14(7):e0220064. doi: 10.1371/journal.pone.0220064

Fig 3. Blood glucose levels of mice transplanted with islets and islets + DPS, and treated with STZ.

Fig 3

Mice were transplanted with 800 human islets (n = 9), with 800 islets + 600 DPS (n = 9), or were non-transplanted (n = 4). At the end of the follow-up, 3 mice transplanted with human islets alone and 6 mice co-transplanted with islets and ductal cells had developed hyperglycemia. Tx indicates transplantation day; STZ: streptozotocin administration; arrow: graft removal. Values are means ± SEM. † p<0.05 vs all other groups (ANOVA and post hoc Tukey’s test on STZ injection days, and days 3, 7 and 11 after last STZ injection); *p<0.05 vs islets group (unpaired Student’s t-test, from day 14 after last STZ injection to the end of study).