TABLE 2.
Additional MANDATE Model Assumptions, Sub-Saharan Africa, 2015
| Assumptions | Value |
|---|---|
| Preterm births in sub-Saharan Africa, N | 3,988,000 |
| Delivery location in sub-Saharan Africa, % | |
| Home | 50 |
| Clinic | 35 |
| Hospital | 15 |
| Antenatal care location in sub-Saharan Africa, % | |
| Home | 30 |
| Clinic | 65 |
| Hospital | 5 |
| Preterm subconditions contributing to preterm mortality, Prevalence | Case fatality rate,a % | |
| Respiratory distress | 20 | 35 |
| Intraventricular hemorrhage | 7 | 7.5 |
| Necrotizing enterocolitis | 1 | 25 |
| Sepsis | 9 | 40 |
| Birth asphyxia | 20 | 20 |
| Preterm with no other conditions | 43 | 2.1 |
| Diagnostics, Baseline penetration | Baseline utilization | Efficacy for Home/Clinic/Hospital, % | |
| Preterm labor51–53 | 50/85/90 | 5/20/35 | 25/80/80 |
| Respiratory distress syndrome46,54 | 50/85/90 | 40/60/95 | 75/95/95 |
| Intraventricular hemorrhage54 | 50/85/90 | 5/40/70 | 25/45/45 |
| Necrotizing enterocolitis54–56 | 50/85/90 | 5/40/70 | 25/85/85 |
| Sepsis49,57,58 | 95/85/90 | 75/80/90 | 75/95/95 |
| Low birth weight59 | 50/85/90 | 5/75/90 | 25/95/95 |
Abbreviation: MANDATE, Maternal and Neonatal Directed Assessment of Technology.
a
The prevalence and case fatality rates assume no preventive or treatment interventions.