Table 1. Secondary Structural Components of Aβ40 in Different States of Its Aggregation as a Percentage of the Total Band Areaa.
| peak no. | center (cm–1) | width (cm–1) | area (%) |
|---|---|---|---|
| Aβ40 Monomer | |||
| 1 | 1696 (3) | 26 (6) | 16 |
| 2 | 1677 (1) | 25 (11) | 61 |
| 3 | 1664 (3) | 24 (46) | 9 |
| 4 | 1650 (12) | 35 (12) | 14 |
| Oligomer | |||
| 1 | 1680 (4) | 29 (2) | 33 |
| 2 | 1666 (0) | 20 (7) | 36 |
| 3 | 1650 (6) | 35 (2) | 31 |
| Fiber | |||
| 1 | 1681 (4) | 20 (5) | 8 |
| 2 | 1665 (0) | 18 (2) | 72 |
| 3 | 1652 (2) | 30 (3) | 20 |
a
Results are obtained via curve fitting of the amide I band of Aβ40 in the Raman spectra of the peptide as a monomer, oligomer, and fiber. Values in parentheses are the standard errors.