Skip to main content
. Author manuscript; available in PMC: 2020 Aug 1.
Published in final edited form as: IUBMB Life. 2019 Jun 17;71(8):1167–1180. doi: 10.1002/iub.2098

Figure 3. Structures of T-box riboswitches.

Figure 3.

(a-c) NMR structures of the B. subtilis tyrS T-box riboswitch domains including the Specifier domain (a; PDB ID:2khy), Specifier and proximal domain with K-turn (b; PDB ID:2kzl), and the antiterminator domain (c; PDB ID:1n53). In (a) and (b), the specifier trinucleotide is shown in red. In (c), green and magenta segments indicate well-ordered and more flexible regions, respectively. (d) Crystal structure of the Stem I distal domain containing the double T-loop motif (PDB ID: 4jrc). (e-f) Co-crystal structures of tRNAGly bound to Stem I from O. iheyensis (e; PDB ID: 4lck) and G. kaustophilus (f: PDB ID: 4mgn). (g) tRNA elbow interaction with the interdigitated double T-loop motif in O. iheyensis Stem I. (h) Codon-anticodon like interaction between the Specifier sequence in Stem I of O. iheyensis T-box and tRNAGly.