Figure 1.
Distribution of 26 CHIP-associated pathogenic mutations identified in the study cohort (A); variant allele fractions (VAF) of mutations (N=26) classified as CHIP, or as variants of unknown significance (VUS, N=101) (B); association between presence of CHIP (C) or VAF of CHIP mutations (D) and time elapsed from completion of chemotherapy; distribution of blood counts among patients with or without detectable CHIP in the study (E); P values from generalized linear models. CHIP: clonal haematopoiesis of indeterminate potential; CI: confidence interval.