Table 2:
HC (n = 16) | PD (n = 18) | ||||||
---|---|---|---|---|---|---|---|
Baseline | Follow-Up | Baseline | Follow-Up | Group effect | Time effect | Group × Time interaction effect | |
Ventral substantia nigra (inferior to red nucleus) | |||||||
pSN | 62.1 (29.1) | 58.8 (25.3) | 113.1 (36.2) | 125.4 (33.4) | < 0.001 | 0.15 | 0.02 |
aSN | 124.0 (38.4) | 116.6 (55.2) | 160.7 (40.4) | 171.8 (55.1) | 0.042 | 0.02 | 0.043 |
Dorsal substantia nigra (adjacent to red nucleus) | |||||||
pSN | 66.9 (23.5) | 68.1 (13.2) | 78.0 (35.0) | 82.3 (28.5) | 0.408 | 0.716 | 0.716 |
aSN | 100.8 (39.4) | 104.2 (33.8) | 111.3 (36.0) | 122.0 (42.2) | 0.716 | 0.655 | 0.428 |
Legend: HC=healthy controls, PD=Parkinson’s disease. Cells represent mean (standard deviation) and are expressed in parts per billion. Group, time and group × time interaction effect values are p-values after correction for the false discovery rate.