Fig. 1.

Study design. a Individuals’ selection flow-chart. b Overview of the viral and host characteristics considered for an association with HIV-1 reservoir size and long-term dynamics during suppressive ART. ART antiretroviral therapy, PBMC peripheral blood mononuclear cells; time of untreated infection was calculated using estimated dates of infection; time to viral suppression was the time taken for viral load to drop below 50 HIV-1 RNA copies/ml plasma; PI protease inhibitor