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. 2019 Jul 19;9:10531. doi: 10.1038/s41598-019-47026-6

Table 2.

SNBRs of PD subjects among the low and high estrogen exposure ratio groups and control groups.

Variables Side Low Eratio group
(N = 31)		 Control-old
(N = 12)		 High Eratio group
(N = 31)		 Control-young
(N = 13)		 p valuea
(Low Eratio vs High Eratio)		 p valuea
(Low Eratio vs Control-old)		 p valuea
(High Eratio vs Control-young)
Anterior caudate More affected side 2.26 ± 0.21 3.62 ± 0.64 2.60 ± 0.20 3.72 ± 0.62 0.424 <0.001 0.002

Less affected

side

 2.59 ± 0.21 3.68 ± 0.66 2.77 ± 0.20 3.80 ± 0.61 0.793 0.003 0.009
Mean 2.48 ± 0.19 3.76 ± 0.61 2.79 ± 0.18 3.14 ± 0.31 0.334 0.001 0.003
Posterior caudate More affected side 1.27 ± 0.14 2.19 ± 0.33 1.41 ± 0.13 2.14 ± 0.42 0.581 <0.001 0.002

Less affected

side

 1.51 ± 0.15 2.27 ± 0.33 1.63 ± 0.14 2.24 ± 0.41 0.793 0.002 0.012
Mean 1.41 ± 0.13 2.23 ± 0.34 1.64 ± 0.13 2.19 ± 0.41 0.332 0.001 0.003
Anterior putamen More affected side 2.38 ± 0.23 4.00 ± 0.50 2.77 ± 0.22 3.01 ± 0.38 0.424 <0.001 <0.001

Less affected

side

 2.69 ± 0.20 4.08 ± 0.53 3.24 ± 0.20 4.12 ± 0.39 0.140 0.002 <0.001
Mean 2.54 ± 0.20 4.04 ± 0.52 3.16 ± 0.20 4.07 ± 0.38 0.096 0.001 <0.001
Posterior putamen More affected side 0.89 ± 0.17 3.66 ± 0.34 1.57 ± 0.17 3.68 ± 0.33 0.027 <0.001 <0.001

Less affected

side

 1.47 ± 0.17 3.74 ± 0.34 2.13 ± 0.17 3.80 ± 0.35 0.054 <0.001 <0.001
Mean 1.18 ± 0.18 3.70 ± 0.34 1.92 ± 0.18 3.74 ± 0.34 0.024 <0.001 <0.001
Ventral putamen More affected side 1.44 ± 0.15 2.99 ± 0.31 2.02 ± 0.15 3.01 ± 0.34 0.027 <0.001 <0.001

Less affected

side

 1.90 ± 0.14 3.14 ± 0.31 2.40 ± 0.14 3.11 ± 0.34 0.057 <0.001 <0.001
Mean 1.68 ± 0.15 3.06 ± 0.30 2.23 ± 0.15 3.06 ± 0.33 0.036 <0.001 <0.001
Ventral striatum More affected side 2.54 ± 0.14 3.02 ± 0.42 2.73 ± 0.14 3.06 ± 0.32 0.424 0.042 0.114

Less affected

side

 2.94 ± 0.16 3.15 ± 0.41 2.97 ± 0.15 3.21 ± 0.29 0.800 0.504 0.320
Mean 2.85 ± 0.16 3.08 ± 0.41 2.98 ± 0.15 3.14 ± 0.29 0.497 0.462 0.461

Data are expressed as mean ± standard deviation.

Abbreviations: SNBRs, Specific to non-specific binding ratios; PD, Parkinson’s disease; Eratio, Estrogen exposure ratio.

aFalse discovery rate-corrected p value of two group comparison.