Table 1.
Genotype frequencies of ANXA5 promoter haplotypes in severe oligozoospermic patients, normozoospermic patients, and control group
| Severe Oligozoospermia (n = 272) | Normozoospermia (n = 269) | PopGen controls (n = 533) | |
|---|---|---|---|
| N/N | 64.0 (174)a | 68.8 (185)a | 77.9 (415)b |
| N/M1 | 10.3 (28)a | 10.0 (27)a | 6.6 (35)a |
| M1/M1 | 0 (0)a | 0.4 (1)a | 0.2 (1)a |
| M1/M2 | 1.5 (4)a | 1.8 (5)a | 0.9 (5)b |
| N/M2 | 23.2 (63)a | 18.2 (49)a,b | 13.5 (72)b |
| M2/M2 | 1.1 (3)a | 0.7 (2)a | 0.9 (5)a |
| M2 carrier rate | 25.7 (70)a | 20.8 (56)a,b | 15.3 (82)b |
The data is presented as % (n). For each row, cells with different superscript letters have significantly different column proportions (p < 0.05)
N the wild-type promoter sequence, M1 the haplotype M1 promoter sequence, M2 the haplotype M2 promoter sequence