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. 2019 Jun 24;45:181–191. doi: 10.1016/j.ebiom.2019.06.023

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© 2019 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 6 — Triple upregulation of TCF7/c-Myc/FOSL1 was a sensitive marker predicting unfavorable prognosis. (A–C) In cohort 1, the overall survival curves were stratified according to c-Myc (A) and FOSL1 (B) expression or triple overexpression of TCF7/c-Myc/FOSL1 (C). (D–F) In cohort 2, the overall survival curves were stratified according to c-Myc (D) and FOSL1 (E) expression or triple overexpression of TCF7/c-Myc/FOSL1 (F). Patients with high expression of TCF7 had poor prognoses, while patients with triple upregulation of TCF7/c-Myc/FOSL1 had much worse prognoses than other patients in both cohort 1 and cohort 2 (P < 0.001 and P = 0.001).