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. 2019 Jul 19;7(14):e14169. doi: 10.14814/phy2.14169

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© 2019 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Top row: Effect of age at stimulator implantation (left) and nonfasted blood glucose concentration at baseline (Glu, right) on changes in nonfasted blood glucose concentration from baseline to follow‐up, adjusted for the respective other confounding factor (ΔGlu_Adj) according to the multiple linear regression analysis shown in Table 2a. Bottom row: Effect of the stimulation on time (left) and stimulation off time (right) on the change in nonfasted blood glucose concentration from baseline to follow‐up, adjusted for the nonfasted blood glucose concentration at baseline and for the age at stimulator implantation (ΔGlu_Adj). Significant linear correlations were found between both stimulation parameters and ΔGlu_Adj. The intersections of the linear trend lines with the zero axes, were located at 20 sec for the stimulation on time and at 179 sec for the stimulation off time.