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. 2019 Jul 2;45:290–302. doi: 10.1016/j.ebiom.2019.06.043

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© 2019 The Authors. Published by Elsevier B.V.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Fig. 3 — Relationship between LAIR1 genotypes/haplotypes and susceptibility to malaria upon enrolment.

Data presented as Odds Ratios (OR) and 95% Confidence intervals (CI) as determined by binomial logistic regression analyses. Covariates in the models included age, sex, HIV-1 and bacteraemia (presence/absence), sickle cell trait, and α-thalassaemia and G6PD status.

(a) Association between LAIR1 genotypes and susceptibility to malaria. None of the LAIR1 genotypes were significantly associated with susceptibility to malaria.

(b) Association between absence (0 copies) and presence (1 or 2 copies) of the haplotypes and susceptibility to malaria. None of the haplotypes significantly altered susceptibility to malaria.

(c) Additive effect of 0, 1, or 2 copies of the haplotypes on susceptibility to malaria. No significant relationships were found for any of the haplotypes.