Table 1.
Characteristics | Sepsis patients (N = 126) |
---|---|
Demographic information | |
Age (y), mean ± SD | 56.6 ± 13.0 |
Gender (male/female) | 83/43 |
BMI (kg/m2), mean ± SD | 23.1 ± 5.5 |
Biochemical index, median (IQR) | |
Scr (mg/dL) | 1.7 (1.2‐2.4) |
Albumin (g/L) | 24.7 (20.57‐32.17) |
WBC (109/L) | 18.4 (3.5‐28.1) |
CRP (mg/L) | 103.6 (52.3‐141.0) |
PCT (ng/mL) | 14.2 (7.8‐24.7) |
Disease severity, mean ± SD | |
APACHE II score | 12.9 ± 5.5 |
SOFA score | 5.1 ± 2.8 |
Inflammatory cytokine, median (IQR) | |
TNF‐α (pg/mL) | 195.0 (119.3‐285.1) |
IL‐6 (pg/mL) | 61.9 (36.5‐132.4) |
IL‐8 (pg/mL) | 54.6 (25.8‐113.1) |
IL‐17 (pg/mL) | 129.4 (71.1‐188.9) |
lnc‐ANRIL relative expression, median (IQR) | 2.56 (1.02‐4.98) |
miR‐125a relative expression, median (IQR) | 0.30 (0.13‐0.59) |
lnc‐ANRIL/miR‐125a axis, median (IQR) | 9.37 (1.87‐24.33) |
Abbreviations: APACHE II, acute physiology and chronic health evaluation II; BMI, body mass index; CRP, C‐reactive protein; IL, interleukin; IQR, interquartile range; PCT, procalcitonin; Scr, serum creatinine; SD, standard deviation; SOFA, sequential organ failure assessment; TNF‐α, tumor necrosis factor‐α; WBC, white blood cell.