Table 2.
Clinical characteristics | lnc‐ANRIL | miR‐125a | lnc‐ANRIL/miR‐125a axis | |||
---|---|---|---|---|---|---|
P value | r | P value | r | P value | r | |
Biochemical index | ||||||
Scr | 0.051 | 0.174 | <0.001 | −0.306 | <0.001 | 0.310 |
Albumin | 0.305 | −0.092 | 0.394 | 0.077 | 0.196 | −0.116 |
WBC | 0.106 | 0.145 | 0.048 | −0.176 | 0.024 | 0.201 |
CRP | 0.002 | 0.273 | 0.001 | −0.289 | <0.001 | 0.335 |
PCT | 0.008 | 0.235 | 0.065 | −0.165 | 0.009 | 0.231 |
Disease severity | ||||||
APACHE II score | <0.001 | 0.291 | 0.001 | −0.292 | <0.001 | 0.354 |
SOFA score | <0.001 | 0.375 | 0.009 | −0.233 | <0.001 | 0.365 |
Inflammatory cytokine | ||||||
TNF‐α | 0.001 | 0.283 | 0.002 | −0.273 | <0.001 | 0.318 |
IL‐6 | 0.243 | 0.105 | 0.002 | −0.276 | 0.010 | 0.229 |
IL‐8 | 0.001 | 0.294 | 0.003 | −0.262 | <0.001 | 0.323 |
IL‐17 | 0.100 | 0.147 | <0.001 | −0.312 | 0.004 | 0.252 |
Correlations were determined by Spearman's rank test. P value < 0.05 was considered significant.
Abbreviations: APACHE II, acute physiology and chronic health evaluation II; CRP, C‐reactive protein; IL, interleukin; PCT, procalcitonin; r, correlation coefficient; Scr, serum creatinine; SOFA, sequential organ failure assessment; TNF‐α, tumor necrosis factor‐α; WBC, white blood cell.